ABSTRACT This article describes the digital critical edition of the works and letters of Nietzsche published by Nietzsche Source compared with the different versions of the Colli/Montinari critical edition.

‘One thing, however, seems certain: the manuscripts should be completely deciphered and transcribed, and studied as a group, as an individual manuscript, as an individual page (in many cases!), and then put in chronological order.For example: yesterday I carefully examined the results of the page by page transcription of the manuscripts of Daybreak. I drew a sort of diagram of all the aphorisms in Daybreak following their appearance in the different manuscripts. Two things came out of this, which are basically (...) the two sides of the same coin, that is: 1) the evolution of Daybreak, and 2) the exact chronology of each manuscript. (shrink)

This article describes the digital critical edition of the works and letters of Nietzsche published by Nietzsche Source compared with the different versions of the Colli/Montinari critical edition.

Der Band verzeichnet erstmals sämtliche Werke und Noten aus Nietzsches persönlicher Bibliothek (BN) bis Anfang Januar 1889. Er listet sowohl die Bestände der Herzogin Anna Amalia Bibliothek als auch die des Goethe- und Schiller-Archivs in Weimar auf. Die kritische Analyse anderer Bestandslisten ermittelte zudem zahlreiche heute nicht mehr vorhandene Titel. Ferner wurden sämtliche Bücherrechnungen und -quittungen von Buchhändlern und Buchbindern ausgewertet, die im Goethe- und Schiller-Archiv aufbewahrt werden. Neben den ca. 2.200 Titeln aus Nietzsches rekonstruierter Bibliothek enthält der Band auch (...) ein Verzeichnis sämtlicher 'Lesespuren' Nietzsches (ca. 20.000), z.B. Anmerkungen, Unterstreichungen und Eselsohren. Ergänzt durch zahlreiche Faksimile-Reproduktionen sowie durch philosophische, historische und bibliographische Einführungen, stellt der Band ein unverzichtbares Arbeitsinstrument jeder zukünftigen Nietzsche-Forschung dar. (shrink)

Introduction: becoming a philosopher -- Traveling South -- A stateless man's passport -- Night train through Mont Cenis -- The camels of Pisa -- Naples: first revelation of the South -- "The school of educators" at the Villa Rubinacci -- Richard Wagner in Sorrento -- The monastery of free spirits -- Dreaming of the dead -- Walks on the land of the sirens -- The carnival of Naples -- Mithras at Capri -- Sorrentiner papiere -- Rée-alism and the chemical combinations (...) of atoms -- The logic of dreams -- An epicurean in Sorrento -- Sacred music on an African background -- The sun of knowledge and the ground of things -- The blessed isles -- The bells of Genoa and Nietzschean epiphanies -- Epiphanies -- The value of human things -- Crossed geneses -- The azure bell of innocence -- Zarathustra's night song -- Epilogue to the bell -- Torna a Surriento. (shrink)

Automne 1876: Nietzsche, jeune professeur de philologie à Bâle, brillant élève de Ritschl, part pour Sorrente, invité par son amie Malwida von Meysenbug. C'est son premier voyage dans le Sud : une découverte qui va changer sa vie et le cours de sa philosophie. C'en est fini des tentatives de renouveler la culture allemande au nom de la cause wagnérienne ; l'auteur de La Naissance de la tragédie (1872) commence sa mue. Paolo D'Iorio dresse la carte de cette métamorphose (...) : lectures et discussions, promenades, explorations des environs avec son ami Paul Rée et l'étudiant Albert Brenner ; il fait revivre cette sociabilité joyeuse et confiante qui fertilise l'élan créateur de Nietzsche. C'est à Sorrente que Nietzsche entreprend la rédaction de Choses humaines, trop humaines, dédié à Voltaire. Cette oeuvre, la première sous forme d'aphorismes, inaugure sa philosophie de la maturité. La rupture avec Wagner qu'il verra alors pour la dernière fois, est intellectuellement consommée bien qu'encore cachée. A la suite de ce voyage, Nietzsche abandonnera sa chaire bâloise et entamera une existence de philosophe sous le signe du Midi entre la Suisse, la France et l'Italie. (shrink)

In his review of my book, Le voyage de Nietzsche à Sorrente, Emmanuel Salanskis writes that it is an agreeable read and philologically precise, but that it presents some philosophical difficulties.The first alleged difficulty lies in the conception of “epiphany.” Salanskis asks, “Can we really include Nietzsche among adherents of an aesthetics of the ‘instant’ (170) like Virginia Woolf ?” No, certainly not. On the page cited, I discuss James Joyce’s conception of epiphany (and mention Virginia Woolf only in passing) (...) in order to distinguish Joycean epiphanies and the aesthetics of the instant from Nietzsche’s epiphanies. The latter, I argue shortly thereafter, are “from an epistemological point of view not moments .. (shrink)

Der Schwerpunkt der Reihe liegt auf thematisch fokussierten Auseinandersetzungen mit Nietzsches Werken, seinen Quellen und seiner Rezeption. Die gehen meist auf Veranstaltungen der Nietzsche-Forschungsstelle Freiburg sowie der Friedrich-Nietzsche-Stiftung Naumburg zurück. Die Reihe ist ideen-, kultur-, literatur- und philosophiegeschichtlich orientiert und - bei Offenheit für disziplinäre Vielfalt - dem Ideal genauer Textlektüren verpflichtet.

Im Mittelpunkt des Bandes steht mit Nietzsches Nachlass derjenige Teil seines Schaffens, von dem seit jeher eine besondere Faszination ausging. Sein Status ist bis heute höchst umstritten. Handelt es sich bei den nachgelassenen Aufzeichnungen um Skizzen und Vorstufen, um Bausteine für neue Werke oder gar – wie etwa Martin Heidegger meinte – um das ‚eigentliche‘ Werk Nietzsches? Außer Frage steht, dass der Nachlass besondere editorische und interpretatorische Schwierigkeiten aufwirft. Zugleich herrscht aber weitgehender Konsens darüber, dass er für das Verständnis von (...) Nietzsches Denken und Schreiben unverzichtbar ist, denn viele seiner zentralen Gedanken sind im Nachlass anders, mitunter scheinbar deutlicher, bisweilen überhaupt nur hier formuliert. Die Beiträge gehen diesen Spannungsverhältnissen nach, indem sie sowohl am Beispiel konkreter Einzelfälle als auch grundsätzlich den angemessenen Umgang mit Nietzsches nachgelassenen Schriften diskutieren. (shrink)

As its title indicates, this book is a study of the trip Nietzsche made to Sorrento in 1876, after the Bayreuth festival and before the publication of Human, All Too Human. Paolo D’Iorio’s main thesis is that at Sorrento Nietzsche became a true philosopher, abandoning his metaphysics of art together with his commitment to the Wagnerian cause in order to develop his philosophy of the free spirit. D’Iorio collects all of the available documents about the Sorrento trip, from Nietzsche’s (...) allusions to his Italian experiences in his notebooks and subsequent works to letters to and from his traveling companions and memoirs of friends and acquaintances. The chief interest of the book lies in this philological work, which .. (shrink)

Quantum cellular automata and quantum walks provide a framework for the foundations of quantum field theory, since the equations of motion of free relativistic quantum fields can be derived as the small wave-vector limit of quantum automata and walks starting from very general principles. The intrinsic discreteness of this framework is reconciled with the continuous Lorentz symmetry by reformulating the notion of inertial reference frame in terms of the constants of motion of the quantum walk dynamics. In particular, among the (...) symmetries of the quantum walk which recovers the Weyl equation—the so called Weyl walk—one finds a non linear realisation of the Poincaré group, which recovers the usual linear representation in the small wave-vector limit. In this paper we characterise the full symmetry group of the Weyl walk which is shown to be a non linear realization of a group which is the semidirect product of the Poincaré group and the group of dilations. (shrink)

The paper aims at proposing an extended notion of epigenesis acknowledging an actual causal import to the phenotypic dimension for the evolutionary diversification of life forms. “Introductory remarks” section offers introductory remarks on the issue of epigenesis contrasting it with ancient and modern preformationist views. In “Transmutation of forms: phenotypic variation, diversification, and complexification” section we propose to intend epigenesis as a process of phenotypic formation and diversification dependent on environmental influences, independent of changes in the genomic nucleotide sequence, and (...) occurring during the whole life span. Then, “Evolvability and phenotypic evolution” section focuses on phenotypic plasticity and offers an overview of basic properties that allows biological systems to be evolvable—i.e. to have the potentiality of producing phenotypic variation. Successively, the emphasis is put on environmentally-induced modifications in the regulation of gene expression giving rise to phenotypic variation and diversification. After some brief considerations on the debated issue of epigenetic inheritance, the issue of culture is considered. The key point is that, in the case of humans and of the evolutionary history of the genus Homo at least, the environment is also, importantly, the cultural environment. Thus, “Bio-cultural feedback” section argues that a bio-cultural feedback should be acknowledged in the “epigenic” processes leading to phenotypic diversification and innovation in Homo evolution. Finally, “Brain plasticity and cultural neural reuse” section introduces the notion of “cultural neural reuse”, which refers to phenotypic/neural modifications induced by specific features of the cultural environment that are effective in human cultural evolution without involving genetic changes. Therefore, cultural neural reuse may be regarded as a key instance of the bio-cultural feedback and ultimately of the extended notion of epigenesis proposed in this work. (shrink)

In this paper we review the general framework of operational probabilistic theories, along with the six axioms from which quantum theory can be derived. We argue that the OPT framework along with a relaxed version of five of the axioms, define a general information theory. We close the paper with considerations about the role of the observer in an OPT, and the interpretation of the von Neumann postulate and the Schrödinger-cat paradox.

I temi della fede e della religione, e del loro conflitto con la cultura laica, sono da qualche tempo al centro di un interesse mediatico crescente, alimentato anche dalle polemiche politiche suscitate dal moltiplicarsi degli interventi e delle "scomuniche" del papa e della Conferenza Episcopale Italiana contro la modernità. Mancava fin qui, tuttavia, un testo di discussione, da punti di vista diversi e reciprocamente problematici, sulle ragioni dell'ateismo e della fede. Un confronto tra gli esponenti di tre posizioni ideologiche molto (...) lontane tra loro, accomunate però dal rifiuto di ogni appartenenza accademica: il cristianesimo nietzschiano del "pensiero debole" di Gianni Vattimo, la saggezza atea di una tradizione antica rilanciata da Michel Onfray e l'empirismo naturalistico-esistenziale della "filosofia del finito" di Paolo Flores d'Arcais. In questo insolito dialogo a tre voci emergono tutti gli interrogativi essenziali legati al problema, a partire da quello più generale: quali devono essere i rapporti tra filosofia e ateismo? L'"ipotesi Dio" deve ormai essere considerata superflua anche dalla riflessione filosofica, visto che le scienze ne fanno metodologicamente a meno? Quali sono le conseguenze etiche e politiche dell'essere atei o, all'opposto, credenti? (shrink)

The theme of the relationship between art and society is certainly not a central topic in the aesthetic reflection of Italian neo-idealism. Neither in Croce nor in Gentile it is ever discussed at length, and the few writings in which it is addressed are brief and polemically oriented. This essay, however, proposes to discuss the few hints present in Croce and Gentile on this subject. First, the debate on the materialistic interpretation of history will be examined, to which both Croce (...) and Gentile made important contributions at the end of the 19th century. Secondly, Croce’s own way of doing the history of literature will be discussed, showing the differences that distance him from the Desanctisian model and also from the model derived from the Hegelian Aesthetics. Croce’s way of making history of literature, indeed, aroused harsh criticism after World War II and provoked a request for a “return to De Sanctis”.Finally, but the theme will be only hinted at in the essay, a brief reference will be proposed to the opinions of Antonio Gramsci and his reading of Croce. (shrink)

After a few general observations on scientific activity, the author briefly comments on different versions of naturalism. Subsequently, he suggests that the birth of evolutionary biology and its successive developments may show how the natural world comes to be differently conceived as scientific advancements are accomplished. Then the main thesis is outlined by introducing the principles of a heuristic science-based naturalism not conclusively defining the real and the knowable. From the epistemological perspective, heuristic naturalism is meant to be framed in (...) critical realism, whereas from the ontological standpoint it may be framed in emergent monism, given that the latter can also underpin recent trends in investigation addressing human specificity. Finally, attention is turned to some implications of heuristically guided scientific activity with regard to the issues of divine action and of imago Dei. (shrink)

This article puts forward some observations about the literary form of Documentalità. The genre to which Documentalità belongs is undoubtedly the philosophical treatise. This is a novelty, because the philosophical treatise is not a popular literary form with contemporary philosophers. But it is a genre that proves to be functional in the project of philosophical reconstruction pursued by Ferraris, and that do not necessarily conflict with the Derridean roots from which Documentality moves.

Fino a vent’anni fa il nome di Solger, uno dei pensatori più significativi del Romanticismo tedesco, certo il più sistematico e filosoficamente attrezzato tra i protagonisti di quella grande stagione, era noto in Italia, anche fra gli studiosi di estetica, quasi soltanto per la menzione che delle sue teorie viene fatta nelle Lezioni di Estetica di Hegel. Nel giro di pochi anni, però, la situazione è radicalmente cambiata. Sono state tradotte le sue Lezioni di estetica, apparse postume nel 182...

Apoptotic pathways have always been regarded as a key‐player in preserving tissue and organ homeostasis. Excessive activation or resistance to activation of cell death signaling may indeed be responsible for several mechanisms of disease, including malignancy and chronic degenerative diseases. Therefore, targeting apoptotic factors gained more and more attention in the scientific community and novel strategies emerged aimed at selectively blocking or stimulating cell death signaling. This is also the case for the TMEM219 death receptor, which is activated by a (...) circulating ligand, the Insulin‐like growth factor binding protein 3 (IGFBP3) and induces a caspase‐8‐dependent apoptosis of the target cells. Interestingly, stimulation of the IGFBP3/TMEM219 axis exerts an anti‐proliferative effect, while blockade of the TMEM219 deleterious signal protects TMEM219‐expressing cells of the endocrine pancreas, lung, and intestine from damage and death. Here, we summarize the most updated reports on the role of the IGFBP3/TMEM219 apoptotic axis in disease conditions, including intestinal disorders and diabetes, and we describe the advancements in designing and testing novel TMEM219‐based targeting approaches in emerging potential clinical applications. (shrink)